Autoimmune Hepatitis Variant: Overlap Syndrome with Primary Biliary Cholangitis

Ugur Ergun, Berkay Kuscu, Merve Nur Ak, Omer Faruk Turan, Elif Nur Avsar, Burak Alp, Ahmet Urk, Burcu Ozkan, Erkan Caglar


Autoimmune hepatitis is a liver parenchymal disease that causes necroinflammatory chronic hepatitis, which is the more common cause of inflammation in women. Serum is characterized by autoantibodies and immunoglobulin height. Primary biliary cholangitis is a chronic cholestatic liver disease characterized by the destruction of intralobular bile duct damage and mostly middle-aged women with the effects of genetic and environmental factors. These two diseases can cause cirrhosis of the liver. In the literature, cirrhotic cases of liver cirrhosis caused by autoimmune hepatitis and primary biliary cholangitis have been reported. In this rare case, which is defined as overlap syndrome, early diagnosis and treatment are important. We present a case of autoimmune hepatitis and primary biliary cholangitis due to overlap syndrome in the etiology of decompensated liver cirrhosis.

Keywords: Liver Cirrhosis, Autoimmune Hepatitis, Primary Biliary Kolangitis

DOI: 10.7176/JSTR/5-6-07

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ISSN (online) 2422-8702