Efficacy of Intraumbilical Vein Injection of Syntocinon on Preventing the Complication of Third Stage of Labor

Abstract

Objective: to evaluate the efficacy of injection of Syntocinon in umbilical vein on preventing the complication of 3rd stage of labor. Study Design: Randomized Control Trail. Study Place and Duration: Department of Gynecology and Obstetrics THQ Samundri, DHQ Khanewal and Nishtar Hospital, Multan from August 2017 to April 2018. Material and methods: Two hundred and thirty eight patients were enrolled for study and were divided randomly into two equal groups, cases and controls. Comparison between the two groups was done on the basis of duration of labor, mean Hb level decrease, difference of Hb before and after six hours of delivery and requirement of manual delivery of the placenta. Comparison between the two groups was carried out by using the Chi square test. Chi square test and independent t test was applied to check the statistical difference between two groups and P value ≤0.05 was considered as statistically significant. Results: Postoperative hemoglobin concentration was 11.53±1.28 g/dl and 11.69±1.06 g/dl in the cases and controls, respectively (p =0.295). Of the cases, 6.7% (8) patients experienced nausea and vomiting, while 4.2% (5) of the controls experienced nausea and vomiting (p =0.392). The difference between groups regarding postoperative hemoglobin levels and the incidence of nausea and vomiting was not statistically significant. There was need for manual placental removal in 4 (3.4%) of the cases and in 15 (12.6%) of the controls (p=0.009). Mean duration of third stage of labor was 5.09 ± 3.01 minutes in the cases and 9.22 ± 4.14 minutes in the controls (p <0.001). The statistically significant difference was observed in the manual removal of placenta and time period of 3^rd stage of labor among the two groups. Conclusion: On clinically administration of Oxytocin into intraumbilical vein immediately after the delivery of the fetus, the overall time period for the 3^rd stage of labor was reduced effectively.

Keywords: Intraumbilical Vein, Syntocinon, Injection, Complications, Postpartum Hemorrhage, Oxytocin, Labor