Effectiveness of Ozone Treatment for Chronic Anal Fistula

Tahoor Ahmed Khan, Rida Fatima, Haseeb Akbar


Objective: To find out if the ozone treatment is promising for chronic anal fistula. Study Design: Non Randomized Trial.Study Location and Duration: General Surgery Department Bahawal Victoria Hospital Bahawalpur. From 20 December 2017 to 28 February 2019. Material and methods: A total of 57 patients were included in our study. Success of the treatment was based upon the cessation of the discharge and closure of the anorectal fistula at the end of the treatment. Statistical analysis was done using computer software SPSS version 23. Mean and standard deviation was calculated for continuous variables like age etc. and frequency and percentage was taken for categorical variables like, gender etc. Comparison of number of sessions for healing and non healing patients was done using a t test. P value of less than or equal to 0.05 was taken as significant. Results: A total of 57 patients presenting with anorectal fistula were included in the study. A total of 19 patients received 60 volume of ozone, 23 received 120 volume of ozone and remaining 15 received 180 volume of ozone. Means and standard deviation of sessions of treatment with ozone was 8.29±3.66. Closure of the fistula was seen in only 14 patients while 43 did not show any improvements or they had reoccurrence of anorectal fistula after getting treatment with ozone.  Conclusion: On the basis of the results of this study, it can be concluded that ozone insufflation is not a promising treatment option for the treatment of anorectal fistula. There were no associated side effects of ozone insufflation. Further studies are required with larger sample size.

Keywords: Ozone Insufflation, Anal Fistula, Enterocutaneous Fistula

DOI: 10.7176/JMPB/55-20

Publication date:May 31st 2019

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ISSN 2422-8427

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