Effects of Bullet Energy Drink on Creatininephosphokinase (CPK) and Lactate Dehydrogenase (LDH) Level of Albino Rat

Abstract

The effects of bullet energy drink on creatinephosphokinase (CPK) and lactate dehydrogenase (LDH) level of albino rat for 28 days were investigated. Wistar albino rats weighing between 100g and 125g were used for the experiment and were divided into 4 groups of 5 rats in each group. The energy drinks was given to the rats orally by intubation except for the control group.  At the end of 7, 14, 21 and 28 days, the mean values for creatinephosphokinase showed statistical increase (p<0.05): (95.003.61; 99.335.03; 13425.74 and 169.674.51) values respectively compared to control (70.671.53, 72.332.52, 73.001.00 and 71.331.53). There was also a statistically significant increase in the, mean value of lactate dehydrogenase: (3166.67152.75, 3900.00100.00, 4545.67767.30 and 2866.33762.85) values compared to control (1870.671.53, 1872.331.53, 1871.331.53 and 1873.673.21). High levels of these parameters indicates that the drink may have an effect of the cardiac muscles. Caution should be exercised when consuming energy drink.

Key Words: creatinephospho kinase, lactate dehydrogenase, wistar