Effect of Uric Acid and Lipid Profile on Myocardial Infarction in Iraqi Population

Abstract

Myocardial infarction is a common presentation of coronary artery disease. This study was aimed to evaluate the effect of uric acid and lipid profile on myocardial infarction in Iraqi population.

The study was conducted on (30) patients acute myocardial infarction, and (30) apparently healthy subjects were taken as control group. The level of uric acid and lipid profile was determined using colorimetric method.

Patient group had significantly higher level of uric acid (P < 0.01), total cholesterol (P < 0.01), triglyceride (P < 0.01), low density lipoprotein (P < 0.01), very low density lipoprotein (P < 0.01) and significantly lower level of high density lipoprotein (P < 0.01) than control group. The results of this study also showed a significant difference (P < 0.01) between males and females regarding uric acid, total cholesterol, triglyceride, low density lipoprotein, very low density lipoprotein and high density lipoprotein in both study groups.

The body weight of the patients demonstrated as body mass index showed a significant association (P < 0.01) with the level of uric acid, total cholesterol, triglyceride, low density lipoprotein and high density lipoprotein in patient group. In conclusion, uric acid may have an effect on precipitating some risk factors of myocardial infarction.

Key words: Uric acid, lipid profile, myocardial infarction.