Correlation between Drug Compliance and Quality of Life in AIDS Patients under Effects of Nursing Intervention

Ming Xu, Jian Wang, Yan Guang Xie, Hui Xin Jin, Qing Meng, Shu Qin Sun, Yang Mei Li, Yu He Yang, Rui Wang


Objective: Good drug compliance is the significant premise of the therapeutic efficacy and the physically healthy level could be reflected by the quality of life. It will be of great importance in enhancing the drug compliance and the quality of life for patients to firm their confidence in fighting with the disease, cooperate with treatment and prolong the lifetime through researching the nursing intervention model for AIDS patients. Based on the analysis of the effects of nursing intervention on AIDS patients’ drug compliance and quality of life, this report studies the correlation between drug compliance and quality of life in AIDS patients under effects of nursing intervention, so as to provide theoretical basis for offering reasonable scheme of nursing intervention more comprehensively, assess the effect of treatment and improve the entirely healthy level of AIDS patients. Methods: A total of 240 AIDS patients were selected as subjects randomly, who were randomized into control group and intervention group, with 120 patients in each group. Both control group and intervention group were given routine nursing measures, while intervention group was given reasonable nursing intervention measures according to nursing requirements on the basis of routine nursing. Baseline data of patients, data after 3 months of observation and data after 10 months of observation were collected using self-made Antiviral Drug Compliance Questionnaire and World Health Organization Quality of Life with 100 Questions (WHOQOL-100), followed by rank correlation analysis and regression analysis. Results: After 3 months and 10 months of nursing intervention, there was obvious rank correlation between patients’ drug compliance and quality of life in the intervention group. After 10 months of nursing intervention, the effects of drug compliance showed obvious gradual enhancement. As for domains of quality of life, after 3 months of nursing intervention, the rank correlation between drug compliance and physiology domain, independence domain and social relation domain became significant; after 10 months of nursing intervention, the rank correlation became more significant, and the rank correlation between drug compliance and psychology domain and environment domain also became significant. Conclusion: Drug compliance has direct influence on the therapeutic effects of patients, and the quality of life can improve the therapeutic effects of patients through influencing patients’ drug compliance. With the continuation of intervention measures, the effects of intervention show gradual enhancement.

Keywords: AIDS; correlation; nursing intervention; treatment compliance; quality of life

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