Antidiabetic Activity of Banana Peel Extract : Effect on Hyperglycemia, Hyperlipidemia and Augmented Oxidative Stress in Diabetes Mellitus

Abstract

Diabetes mellitus is one of the common metabolic disorders acquiring around 2.8% of the world's population and is anticipated to cross 5.4% by the year 2025. In 2012, the number of diabetes sufferers in Indonesia ranked as the seventh largest number of diabetics as many as 7.6 million and according to the WHO the prevalence of diabetes cases will continue to rise up to 154% in 2030. Since long back herbal medicines have been the highly esteemed source of medicine therefore, they have become a growing part of modern, high-tech medicine. From the review it was suggested that banana peel contained large amounts of dopamine and L-dopa, catecholamines with a significant antioxidant activity. The banana peel also shown the ability as antioxidants to prevent the oxidation of fish oil and might be considered as rich sources of natural antioxidant. Thus, from the review majorly, the antidiabetic activity of banana peel is attributed to the presence of pectin (10-21%), lignin (6-12%), cellulose (7,6- 9.6%), and hemicellulose (from 6.4 to 9.4%) which show reduction in blood glucose levels. Another research shown that pectin can also against hypercholesterolemia with decreasing total cholesterol, LDL cholesterol and HDL cholesterol.

Keywords: Banana Peel Extract, Antidiabetic activity, Diabetes mellitus, Pectin