Detection of Chlamydia trachomatis Immunogloblins in Seminal Plasma by Microimmunofluorescence Test and Their Effect on Semen Parameters of Infertile Males in Iraq

Abstract

Background: There is controversy over the role of asymptomatic genital tract infection of Chlamydia trachomatis (C. trachomatis) in the etiology of male infertility.

Aim of the Study: Detection of chlamydia antibodies in seminal plasma of infertile men and its effect on semen parameters.

patients and Methods : Semen samples were collected from 144 infertile male, 35 normal fertile male ,seminal plasma was used for detection of chlamydia antibodies by Microimmunofluorescence test (MlF) using species-specific antigens (genital serotypes D-K)

Results: This study confirmed that antichlamydia lgA and/ or lgG that were detected in seminal plasma of infertile males appeared to be C. trachomatis specific and associated with an inflammatory response. Semen parameters were severely affected in infertile patients with positive titer of antichlamydia lgA and or lgG that were detected in seminal plasma.

Conclusions: chlamydia trachomatis play an important role in male infertility

Keywords: C. trachomatis, infertility, immunoglobulines, semen parameters, microimmunofluorescence test