Microwave Assisted Synthesis, Characterization and Biological Study of Some Chalcone Compounds Derived from Phenyl Isothiocyanate

Abstract

Chalcones are synthesized by Claisen-Schmidt condensation, which involves cross-aldol condensation of appropriate aldehydes and ketones by base catalyzed reaction, the new chalcone derivatives synthesized by the reaction aldehyde with their compounds. By microwave assisted synthesis, a considerable increase in the reaction rate has been observed and that too, with better yields. M.P., TLC, CHN, FTIR, NMR and MS spectroscopy has characterized all the synthesized compounds. The biological screening data of the synthesized compounds were also studied.

Keywords: microwave, chalcone, antibacterial.

DOI: 10.7176/CMR/11-3-05

Publication date:March 31^st 2019