Synthesis ,characterization and antibacterial activity of mixed ligand complexes of some metals with 1-nitroso-2-naphthol and L-phenylalanine

Abstract

The mixed ligand complexes of Mn(II),Fe(II),Co(II),Ni(II),Cu(II), Zn(II) and Cd (II) with 1-nitroso-2-naphthol (C₁₀H₇NO₂), symbolized (NNPhH)] and amino acid L-phenylalanine( C₉H₁₀NO₂), symbolized (phe H),  were synthesized and characterized by: Melting points, Solubility, Molar conductivity. determination the percentage of the metal in the complexes by flame(AAS), Molecular weight determined by  Rast’s Camphor method, susceptibility measurements, Spectroscopic Method [FT-IR and UV-Vis], And Program  [Chem office– CS .Chem.– 3D pro 2006] was used for draw compounds . The results showed that the deprotonated   two  ligands acts as a bidentate ligand ,  (phe^-) was coordinated to the metal ions through the oxygen  of  the  carboxylic  group  and  the nitrogen of the amine and  the 1-nitroso-2-naphthol ligand was coordinated to the metal ions through the oxygen and nitrogen atoms. The electronic absorption spectra and magnetic susceptibility measurements of the complexes indicate octahedral geometry for all the complexes.

Key words: phenyl alanine , amino acid) Complexes ,  1-nitroso-2-naphthol  ,mixed ligands   and Antibacterial     Activities