https://www.iiste.org/Journals/index.php/JMPB/issue/feedJournal of Medicine, Physiology and Biophysics2024-02-17T06:23:08+00:00Felix LauJMPB@iiste.orgOpen Journal Systems<p>The journal is a peer-reviewed, international and interdisciplinary research journal. The scope of the journal includes, but not limited to, mechanisms in medicine, technology and manufacturing of medicines, diagosis, surgery, healthcare, scientific study of function in living systems, interdisciplinary sciences using methods of, and theories from, physics to study biological systems from the molecular scale to whole organisms and ecosystems.</p><p> </p><p><strong>Editorial Board of the journal</strong></p><span id="docs-internal-guid-d1b5aa83-7fff-423d-a928-5a3cb8369c36"><p dir="ltr"><span>Prof. Dr. Ignat Ignatov DSc: Scientisic Research Center of Medical Biophysics, Bulgaria</span><span><br /><br /></span></p><p dir="ltr"><span>Hugo Niggli DSc: Institue BioFoton AG, Switzerland</span><span><br /><br /></span></p><p dir="ltr"><span>Ass. Prof. Iliana Yaneva MD: National Center of Public Health and Analyses</span><span><br /><br /></span></p><p dir="ltr"><span>Dr. Yuliana Pesheva MD (medicine) MSc (biotechnology): Scientific Research Center of Medical Biophysics,Thessaloniki, Greece</span></p><br /><p dir="ltr"><span>Ass. Prof. Georgi Gluhchev PhD: Bulgarian Academy of Sciences</span></p></span><p> </p><p><strong>About the Chief Editor of the journal</strong></p><p>Prof. Ignat Ignatov was born on January 1, 1963 in Bulgaria. In 1989 he majored in physics from “Kliment Ohridski” Sofia University and in the same year he began his professional work in the sphere of medical biophysics. In 1996 he founded the Scientific and Research Center of Medical Biophysics (SRCMB). From 2007 Ignat Ignatov is honorable doctor in European Academy of Natural Sciences (Germany). From 2013 he is Doctor of Science and Professor in The Russian Academy for Natural History.</p><p> </p><p>Index of this journal: EBSCO (U.S.) Index Copernicus (Poland) Ulrich's Periodicals Directory (ProQuest, U.S.) JournalTOCS (UK) PKP Open Archives Harvester (Canada) Bielefeld Academic Search Engine (Germany) Elektronische Zeitschriftenbibliothek EZB (Germany) SCI-Edge (U.S.) Open J-Gate (India) OCLC WorldCat (United States) Universe Digtial Library (Malaysia) NewJour (Georgetown University Library, U.S.) Google Scholar The IC Impact factor value of this journal is 2.24</p><p>IISTE is a member of <a href="http://www.crossref.org/01company/17crossref_members.html">CrossRef</a>.</p><p>The DOI of the journal is: https://doi.org/10.7176/JMPB</p><p> </p>https://www.iiste.org/Journals/index.php/JMPB/article/view/62074Journal coverpage2024-02-17T06:23:08+00:00Journal Editord@d.comJournal coverpagehttps://www.iiste.org/Journals/index.php/JMPB/article/view/62075Nurses Practice and Associated Factors towards Hemodialysis Care in Addis Ababa, Ethiopia2024-02-17T06:23:08+00:00Mesay Bifad@d.com<p><strong>Background: </strong>Patients on hemodialysis care are at a greater risk of developing infectious diseases that leads to life treating complications. The deficiency in practice of nurses when caring for patients who are in hemodialysis has a negative effect on the improvement of the patient's condition. This study was conducted to determine nurse’s practices and associated factors towards dialysis care.<strong>Methods: </strong>An<strong> </strong>institution based cross-sectional study was employed in this study. A total of 62 nurses giving hemodialysis care were included. Statistical analysis was performed using SPSS version 26.0 software. Frequency with percentage was used to report categorical variables, while mean with standard deviation was used to report quantitative variables. Adjusted odds ratio with 95% confidence interval was used to identify factors associated with the outcome variable in the logistic regression model, considering P<0.05 to declare statistical significance.<strong> Result: </strong>In this study, about 65% of nurses working in the dialysis unit had good practice.<strong> </strong>Nurses years of experience [AOR: 11; 95% CI (1.29-39.3)], having training [AOR: 8.5; (95% CI; 2.26-27.5)], knowledge [AOR: 12 95% CI: 2.65-56.2)] were significantly associated with the practice of nurses regarding hemodialysis care.<strong>Conclusion:</strong> In this study we found that the nurse’s practice towards hemodialysis service was good. Training, experience and knowledge of nurses were significantly associated with the experience towards hemodialysis care. Thus, interventions should focus on improving experience, awareness and training of nurses to improve the practice of nurses regarding hemodialysis care.<strong></strong></p> <p><strong>Keywords: </strong>Hemodialysis, Nurses, practice, Associated factors</p> <p><strong>DOI:</strong> 10.7176/JMPB/74-01</p> <p><strong>Publication date: </strong>January 31<sup>st</sup> 2024</p>https://www.iiste.org/Journals/index.php/JMPB/article/view/62076Role of Adipoq Rs 266729 Gene Polymorphism with Risk of Type 2 Diabetes Mellıtus: Case Control Study2024-02-17T06:23:08+00:00Serdal Tarhaned@d.com<p class="Default"><strong>Objectıve:</strong> The aim of the study is to reveal the relationship between adiponection gene variants type 2 diabetes, in diabetes, which has become a majör problem in the twenty-first century. <strong>Materıals and Methods:</strong> This case-control study included 100 patients (60 men and 40 women) with type 2 diabetes treated at Musayyib Hospital and 100 healthy volunteers of the same age and gender to serve as a control group for the study. In the study, DNA was extracted from blood and genotyped by PCR-RFLP and also clinical features of diabetes (Fasting glucose, HbA1c and Lipid profile) were investigated. <strong>Results:</strong> Compared to patients without diabetes, the frequency of the G allele of the rs266729 polymorphism was found to be significantly higher in diabetic participants. In addition, the homozygous GG genotype greatly increased the risk of Type II diabetes. <strong>Conclusıon:</strong> The heterozygous genotype (GC\CG) was associated with a twofold increased risk of type II diabetes compared to the wild type (CC), and although there was no significant difference in the clinical features of diabetes according to adiponectin genotypes, there was a significant difference in fasting glucose, HbA1c and lipid profile between patients and controls. In the Iraqi population, the adiponectin gene polymorphism rs266729 has been linked to Type II diabetes, with people with the heterozygous genotype (GC\CG) being significantly more likely to develop Type II diabetes.</p> <p><strong>Keywords: </strong>Adiponectin, Gene polymorphism, Type 2 diabetes,</p> <p><strong>DOI:</strong> 10.7176/JMPB/74-02</p> <p><strong>Publication date: </strong>January 31<sup>st</sup> 2024</p>https://www.iiste.org/Journals/index.php/JMPB/article/view/62077Self-Care Practice and Associated Factors among Ambulatory Heart Failure Patients in Selected Public Hospitals of Sidama Regional State Ethiopia, 20222024-02-17T06:23:08+00:00Amanuel Fantad@d.com<p><strong>Background: </strong>Heart failure (HF) is a new issue that is significantly undergoing epidemiological change in low to middle income nations. Proper self-care is linked to better overall health and quality of life, improved clinical results, lower healthcare expenditures, and prevention or early identification of health issues in people with chronic conditions like Heart Failure (HF). Unfortunately, inadequate self-care is frequent among heart failure patients, and individuals find it extremely challenging to undertake self-care<strong>.Objective:</strong> The study was conducted to assess the Self-care Practice and Associated factors among Ambulatory Heart Failure Patients in Public Hospitals of Sidama Regional State, Ethiopia, 2022.<strong>Methods:</strong> Institution based Cross-sectional study was conducted in Public Hospitals of Sidama Regional State, Ethiopia from April, 2022 to May, 2022. The data was collected from Eligible participants by face-to-face interview while they are visiting a cardiac clinic to attend their follow ups using pre-tested structured questionnaire. Systematic Random Sampling method was employed to obtain the desired Sample Size. Data was coded and entered into Epi-data version 4.62 then exported to SPSS version 25.0.A Bivariate and Multivariable Logistic Regression Analysis was used to check the significant association of factors with the outcome variables.<strong>Results</strong>: The overall Prevalence of Good self-care Practice was 136 (52.7%) at 95% CI: (46.6, 58.7). The heart failure patients who had poor level of knowledge about self-care practice [AOR=2.434, 95% CI (1.086, 5.453)], Current alcohol drinker [AOR=3.681, 95% CI (1.075, 12.600)], Co-morbidities [AOR=2.463, 95% CI (1.150, 5.276)], were associated with poor or inadequate self-care practice as recommended as compared to their counter parts.<strong>Conclusion:</strong> Nearly half of the heart failure patients had poor self-care practice. Being current alcohol drinker, having Co-morbidity and Inadequate knowledge were predictors of self-care practice. As a result, nursing intervention programs regarding knowledge on heart failure are recommended for enhancing self-care practices. <strong></strong></p> <p><strong>Keywords: </strong>Self-care practice, Heart failure knowledge, Associated factors,sidamma.</p> <p><strong>DOI:</strong> 10.7176/JMPB/74-03</p> <p><strong>Publication date: </strong>January 31<sup>st</sup> 2024</p>https://www.iiste.org/Journals/index.php/JMPB/article/view/62078Prevalence, Associated Risk Factors and Major Bacterial Pathogens Causing Bovine Mastitis on Selected Dairy Farms in and Around Harar, Ethiopia2024-02-17T06:23:08+00:00Amedine Shafid@d.com<p><strong>Aim: </strong>Mastitis, an inflammation of the mammary gland, is a complex and costly disease in dairy herds. The main aim of this study was to estimate the prevalence of mastitis and associated risk factors for bacterial pathogens in lactating dairy cows.<strong>Methods: </strong>A cross-sectional study was carried out. The study was conducted in Harar town and its district from November 2016 to April 2017. A total of 384 (264 crossbreds and 120 Holstein Frisian) milking cows were tested using the California Mastitis Test (CMT), direct diagnosis of obverse clinical mastitis, and bacterial culture in Harar City and its district.<strong>Results: </strong>The result of the study indicated the prevalence of mastitis at the cow level was 58.60% (225/384), out of which 10.7% (41/384) and 47.9% (184/384) were clinical and subclinical, respectively. The quarter-level prevalence was 34.1% (513/1536); from this, the clinical and subclinical forms were 8.7% (131/1536) and 25.4% (382/1536), respectively, while 2% (31/1536) had blind teats. From 341 culture-positive samples, the following bacteria were isolated: Out of the total, Coagulase-negative Staphylococcus (CNS) (28.5%) was the most prevalent isolate, followed by <em>Streptococcus species</em> (27.5%), <em>S. aureus</em> (21.4%), <em>E. coli</em> species (14.4%), <em>Micrococcus species </em>(5.3%), and <em>Corynebacterium species</em> (2.9%). Age, parity, breed, production, and hygiene were significant associated risk factors, whereas management risk factors such as house types, milking systems, farming systems, and treatment history do not have a significant association with the prevalence of mastitis in the study area at this level of significance.<strong>Conclusion: </strong>Based on the findings of this study, thorough screening of high producing and aged cows should be needed; optimum space should be required for those cows kept in intensive and closed houses to reduce the risk of contagious mastitis; attention should be paid to the informal use of drugs; and further research should be needed to view other risk factors for mastitis.<strong></strong></p> <p><strong>Keywords:</strong>Bovine mastitis, Prevalence; Risk factors, Major bacterial pathogens</p> <p><strong>DOI:</strong> 10.7176/JMPB/74-04</p> <p><strong>Publication date: </strong>January 31<sup>st</sup> 2024</p>