Study of GPCR levels in Iraqi diabetic and diabetic nephropathy

Abstract

Abstract

Aim of the study is to determined  G-protein coupled receptor levels in diabetic and diabetic nephropathy patients and compare the results with control group. Study also, aimed   to find relationship  of GPCR with HbA1c , cholesterol and Triglyceride  in these patients ,in order to  that GPCR could be used as a marker combat diabetes and its complication . One hundred fifty subjects were involved  in this study that divided into three groups as follows:- Control group (G1) consists of 50 healthy individuals. Diabetic group (G2) consists of 50 patients and diabetic Nephropathy group (G3) consists of 50 patients . levels of HbA1c % , urea , createnine , albumin , TC, TG, HDL-c, LDL-c , VLDL-c and GPCR were determined in all subjects. Conclusion could be drawn from study that the difference between GPCR levels among  groups indicate GPCR may be used as a marker in development of diabetic nephropathy as well as their  are a significant relation for GPCR with TC and TG .

Keywords: GPCR , diabetic and diabetic nephropathy