A Review: An Overview on Synthesis of Some Schiff bases and there Metal Complexes with Anti-Microbial Activity

Abstract

Azomethine linkage of Schiff base play an important role in medical field with so many pharmacological activities such as antimicrobial, antiviral, ant tubercular and anticancer activity. The potency of these pharmaceutically useful drugs in treatment of microbial infections and other activities encouraged the development of some more potent and significant compounds and metal complexes.

Schiff bases and there metal complexes are remarkably effective compounds, extensive biochemical and medicinal studies have confirmed that these molecules are effective against various strains of microorganisms. This review is summarized to know about the chemistry of different derivatives of substituted Schiff bases and there metal complexes with various metals along with their anti-microbial activities.

Key words: Substituted Schiff bases, Metal complexes, Anti-microbial activities.