Isolation, Structural Elucidation of Alkaloid Constituent and Antimicrobial Activity of Methanol Extract from Berries of Embelia Schimperi

Abstract

The main target of this project is that to investigate chemical constituent and evaluating antibacterial activities of methanol extract from berries of Embelia schimperi. Chromatographic separation of a methanol extract from berries of the plant led to isolation of 2-(pent-4-ol)-N-methyl cyclohexylamine (F₃). The study revealed that the crude extracted berries of the plant have a wide MIC range of 4.22 to 20.14 mg/mL against all tested bacteria strains.

Keywords: Embelia schimperi, 2-(pent-4-ol)-N-methyl cyclohexylamine, antimicrobial activity and methanol