Microwave Assisted Synthesis, Characterizations and Antibacterial Activity of Some of Thiazole Schiff Base and Azetidinone Derivatives

Abstract

A series of substitution thiazole Schiff base (SB1-SB12) were synthesis by reaction substitution phenyl 2-amino thiazole with 4-N,N-dimethyl benzaldehyde Azetidinone (AZ1-AZ12) were also synthesised by reaction substitution thiazole Schiff base with acetyl chloride. The synthesis compounds have been characterized by M.P., TLC, CHN, UV, FT-IR, ¹HNMR,¹³CNMR and MS. The biological screening data of the synthesized compounds were also studied.

Keywords: Microwave, Thiazole, Schiff base, Azetidinone, Anti-bacterial